Date: July 19, 1985
Time: 03:43
Location: Near Erie, Pennsylvania
Operator: Air Ohio - Air Taxi
Flight #: 21
Route: Louisville, KY - Cleveland, OH
AC Type: Aerostar 601
Registration: N71MA
cn / ln: 61-0217-094
Aboard: 2   (passengers:1  crew:1)
Fatalities: 2   (passengers:1  crew:1)
Ground: 0
Summary: During a normal IFR cruise flight, the pilot of Air Ohio Flight 21, did not respond to ATC instructions. Air Ohio flight 21 continued for 40 minutes with no reply and without deviation in altitude or heading until the discrete target disappeared from radar over Lake Erie. The pilot had not slept for approximately 30 hours prior to the loss of communication response.

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